Managing Eye Health for People With Diabetes

This wiki is for patients and health-care workers wanting to learn more about management of diabetic retinopathy.

Latest Topics

Studies: Aflibercept 8 mg for DME (PHOTON trial)

The Study of a High-Dose Aflibercept in Participants With Diabetic Eye Disease (PHOTON) met its primary endpoint of patients with diabetic macular edema (DME) patients maintained on 12 and 16 week intervals between injections of  a unique formulation of aflibercept (8 mg). This 8 mg dose four-fold higher than Eylea (2 mg). Key result was […]

Research news: TRPV2 reduction contributes to loss of blood flow autoregulation in diabetic retinopathy eyes

A study conducted on rats at Queen’s University in Belfast, UK has found that the downregulation of TRPV2 channels in retinal vessel walls is at least partly responsible for the loss of blood flow autoregulation in the retina and the formation of diabetic retinopathy symptoms.     Diabetic retinopathy is a leading cause of vision […]

Research news: PANORAMA study shows improvement in diabetic retinopathy severity with anti-VEGF injections

The results of the PANORAMA Study suggest that injection of anti-VEGF drugs into eyes with moderate to severe NPDR reduces the risk of progression to vision-threatening complications. Diabetic retinopathy is a leading cause of vision loss in adults. Current treatments are described here. Regular intravitreal injection of anti-VEGF drugs reduces the severity of both proliferative […]

Research news: Garlic tablets may reduce DME

The results of a small, double-blinded clinical trial suggest that garlic tablets, taken orally, may be an effective complementary therapy for patients with diabetic macular edema (DME) from diabetic retinopathy (DR). Diabetic macular edema is a leading cause of vision loss in adults. Current treatments are described here. Garlic has been shown to have antidiabetic […]

Diabetic macular edema (DME): Treatment with micropulse laser surgery

DME is typically treated with anti-VEGF or triamcinolone steroid injections. For patients who respond poorly or wish to avoid intravitreal injections, laser treatment can be performed. There are two types of laser treatment used to reduce the leakage of fluid from blood vessels that leads to DME:  Photocoagulation. This is where the laser is used […]

anti-VEGF drugs: brolucizumab (Beovu)

Brolucizumab (trade name Beovu) was the third anti-VEGF drug approved by the FDA for treatment  of DME. The package insert is currently located here. Brolucizumab -dbll is an inhibitor of vascular endothelial growth factor (VEGF) like the other anti-VEGF drugs. It is a humanized monoclonal single-chain variable (Fv) antibody fragment. As such it has a small […]

About the Authors

Albert O. Edwards MD, PhD Albert O. Edwards, MD, PhD is a board certified ophthalmologist who has been practicing medicine for over 20 years. His expertise has been recognized by several agencies and publications including the list of Best Doctors in America. His practice focuses on premium cataract surgery and management of diseases affecting the back of the eye such as macular degeneration, diabetic retinopathy, uveitis, and eye tumors. In addition to extensive training in medical and surgical ophthalmology, Dr. Edwards has fellowship training and extensive medical and surgical experience in medical retinal disease, vitreoretinal surgery, uveitis, and ocular tumors. His research has been published numerous times and he holds faculty appointments at both the Oregon Health & Science University and the University of Oregon. Prior to moving to Eugene in 2009, Dr. Edwards was a faculty member at the Mayo Clinic in Rochester, MN.
Justin Etzel MD Justin Etzel, MD was raised in the Willamette Valley and initially discovered his interest in medicine in high school while working as a clinic assistant at a local optometry office. He earned his Bachelor of Arts degree in Biology from Willamette University in 2012, where he completed his thesis research as a Murdock Scholar at the Oregon Health & Sciences University studying embryonic development. He then spent two years working as a research scientist at the University of Washington in Seattle before attending medical school at the Penn State University College of Medicine. His interest in eye care grew while in medical school as he participated in research projects aiming to uncover the origins of Age-Related Macular Degeneration, before graduating in 2018. Dr. Etzel completed his internal medicine internship at Sinai Hospital in Baltimore, Maryland and his ophthalmology residency at the Geisinger Medical Center in Danville, Pennsylvania before moving back to Oregon to provide comprehensive ophthalmologic care. Outside of practicing ophthalmology, Dr. Etzel enjoys cycling and photography, and spends most of his free time with his wife and two Vizslas camping, hiking, and traveling outdoors.
Ryan Lebien Ryan Lebien, MBA has over 10 years of experience in the clinical and biomedical research industry. His experience includes overseeing a growing ophthalmologic clinical trials program in Eugene, OR and consulting as a Clinical Research Associate for ophthalmology trials all over North America.